Richard Lopata
Department / Institute
Group
RESEARCH PROFILE
Richard Lopata is an Associate Professor at the TU/e research group Cardiovascular Biomechanics (department of Biomedical Engineering) where he leads the PULS/e lab, Photoacoustics & Ultrasound Laboratory Eindhoven. The PULS/e lab facilitates research on technology development, such as ultrasound functional imaging, photoacoustics and image-based modeling; and more applied science, in particular ultrasound-based biomechanical modeling for improved clinical decision making.
In his research, Richard Lopata aims amongst others at the ultrasonic characterization of vulnerable arteries, such as aneurysms and plaques. A patient-specific biomechanical model of these arteries may help to better assess rupture risk, and ultrasound has the ability to provide highly detailed information on plaque geometry and distensibility. A second research line concerns the development and testing of 2-D and 3-D ultrasound imaging techniques for the assessment of cardiac function. The focus here is on acquisition, algorithms and methods that process the (raw) ultrasound data to produce measurements, needed in the clinic, and on methods to validate these measurements. These functional imaging techniques include motion/strain imaging, flow imaging and multi-perspective ultrasound imaging. Recent efforts are aimed at the assessment of cardiac function during exercise, together with USONO (spin-off company).
Photoacoustic imaging techniques, aimed at skin disease and plaque vulnerability assessment, are developed and validated in a preclinical setting.
Close collaborations with both clinical and technical partners were established over the years, paramount for a successful translation of these techniques from bench (lab) to bedside (clinic).
ACADEMIC BACKGROUND
Richard Lopata studied BioMedical Engineering at Eindhoven University of Technology (TU/e, The Netherlands) and received his MSc in 2004 on pharmacokinetic parameter estimation in dynamic contrast-enhanced MRI. From 2004-2009, Richard performed PhD research at the Clinical Physics Laboratory of Radboudumc (Nijmegen, The Netherlands), resulting in his PhD thesis on '2D and 3D Ultrasound Strain Imaging: Methods & In Vivo Applications'.
The following two years,he was a postdoctoral researcher at Maastricht University Medical Center (The Netherlands) and TU/e. In this period he was awarded a NWO-TTW VENI grant (2011).
In 2012, he became an assistant professor at TU/e. He works at the TU/e research group for Cardiovascular Biomechanics (department of Biomedical Engineering). Lopata founded the Photoacoustics and Ultrasound Laboratory Eindhoven, PULS/e. in 2014. In this period, Lopata was granted several EU-funded grants (FP7, H2020) and national grants.
In January 2017, he was appointed associate professor, receiving an ERC starting grant later that year. He has graduated over 35 MSc students and 1 PhD student, and is currently supervising 9 PhD students, two post-docs and 10 MSc students.
Recent Publications
-
Jan-Willem Muller,Hans-Martin Schwab,Min Wu,Marcel C.M. Rutten,Marc R.H.M. van Sambeek,Richard G.P. Lopata
Enabling strain imaging in realistic Eulerian ultrasound simulation methods
Ultrasonics (2023) -
Esther J. Maas,Arjet H.M. Nievergeld,J.H.C. Fonken,Mirunalini Thirugnanasambandam,Marc R.H.M. van Sambeek,Richard G.P. Lopata
3D-Ultrasound Based Mechanical and Geometrical Analysis of Abdominal Aortic Aneurysms and Relationship to Growth
Annals of Biomedical Engineering (2023) -
Judith Fonken,Esther Maas,Arjet Nievergeld,Marc van Sambeek,Frans van de Vosse,Richard Lopata
The Impact of a Limited Field-of-View on Computed Hemodynamics in Abdominal Aortic Aneurysms
Annals of Biomedical Engineering (2023) -
Vera H.J. van Hal,Jan-Willem Muller,Marc R.H.M. van Sambeek,Richard G.P. Lopata,Hans Martin Schwab
An aberration correction approach for single and dual aperture ultrasound imaging of the abdomen
Ultrasonics (2023) -
Hein de Hoop,Hans-Martin Schwab,Richard G.P. Lopata
Coherent Bistatic 3-D Ultrasound Imaging using Two Sparse Matrix Arrays
IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control (2023)
Current Educational Activities
- Imaging
- Ultrasound in the (bio)medical engineering
- Measurements and modeling in the clinic
- Systems in time and space
- Medical ultrasound
- Advanced imaging techniques
- Advanced topics in Ultrasound imaging in the (bio)medical engineering
- Imaging
- Linear algebra & multivariable calculus
- Clinical measurements & signal processes
- Dynamic systems
Ancillary Activities
No ancillary activities