Projects
Bachelor End Projects (BEPs)
BEP projecten starten in onze groep in kwart 4. De projecten sluiten aan bij lopende onderzoeken, waarover je hier meer informatie kunt vinden.
Voor meer informatie kun je mailen naar bep.stbe@tue.nl
Evaluation of RNA silencing plasmids for Notch signalling modulation
One of the methods to study the role of a protein is silencing through RNA interference. With silencing one blocks the production of a…
MRI based 3D finite element modelling of deep tissue injury
What are the histological effects of loading muscles tissue?
The goal of this study is to determine the physiological response of the muscle to loading using histology. Tibialis anterior muscles which…
Measuring shear stress
Modelling skin viscoelasticity
Biodegradable electrospun cardiovascular prosthesis: accelerated degradation and mechanical characterization in vitro
This project intends to characterize PCL-based materials for cardiovascular implants, and measure some of their most relevant mechanical…
Successful protection against cancer
Numerical algorithms to predict cellular traction forces
Mechanical testing of soft biological tissues
In this project, we would like to compare two methods of mechanical testing: our proposed (non-destructive) bulge test method, to a standard…
Vascular graft endothelization: a way towards improved hemocompatibility?
The aim of this project is to characterize the growth dynamics and phenotype of ECs seeded on novel electrospun materials with different…
The influence of heart valve geometry on long-term functionality
A finite element framework is readily available in which the student can generate finite element meshes with different valve geometries by…
Unraveling cross-talk between macrophages and (myo)fibroblasts for in situ tissue engineering
Controlling cell adhesion to functionalized surfaces
Incorporation of antibacterial agents in artificial vascular access grafts for haemodialysis
Master thesis projects
The STEM group provides a monthly information and consultation meeting for (future) master students.
The meetings are hosted by two of our staff members and take place during a Monday lunch hour, somewhere in the Gemini building (mostly in the CIC).
Mimicking kidney lumens by 2-photon laser ablation in hydrogels
In this student project assignment, you will get the opportunity to work and learn in both Microfab/Lab and Laboratory for Cell and Tissue…
Tissue engineering of the corneal stroma by simultaneously guiding the overall tissue shape and architecture of collagen.
Stiffness measurement for cardiac microtissues, the effect of stiffness on tissue contractility
In this project, you will explore the possibilities of measuring microtissue stiffness and develop a protocol for these measurements. When…
Biomechanical properties of the prolapsed vagina wall in women
The aim of the study is to assess structure-function properties of vaginal wall tissue of women with a POP, where mechanical properties…
Tissue engineering solutions for the lower urinary tract
This project emphasizes on the feasibility of new tissue engineering techniques and technologies to support the regeneration and function of…
Pull it like a cell
In this Master’s research project, you will explore the possibilities of circumventing these challenges by developing a novel technique to…
Immunoengineering: Elucidating the influence of biophysical and biomechanical cues on human macrophages
In situ TE (TE) is a new approach for obtaining living replacement grafts for damaged heart valves and blood vessels, superior to existing…
Modeling cell mechanosensing
In this Master’s research project, you will use a finite element modeling based on the tensegrity approach to describe the biomechanical…
Influence of prolonged heart valve storage on donor valve functionality and durability
In this Master’s research project, you will study several human aortic heart valves that have been stored in either liquid nitrogen (-196°C)…
The role of hemodynamic loading on the link between vimentin and Notch signaling
In short, the aim of the project is to create vimentin knock out vascular cells to study the relation between vimentin, Notch signalling and…
The effect of cell mechanics on valvular cell fate
In this project you will study the interplay between mechanical (hemodynamic) cues the cells are exposed to and the cell-cell interactions…
Why is cell therapy for cardiac regeneration still a myth? A 3D cardiac hydrogel model system to unravel the myth
In this Master Thesis Project, the goal is to develop a method to create a 3D hydrogel culture system with both anisotropic and isotropic…
Keratocyte alignment and ECM production under influence of in vivo-like cues
One of the characteristics of the stromal layer is the fact that keratocytes develop and maintain the surrounding collagen lamellae in an…