Precision Medicine
The Precision Medicine group focuses on designing and evaluating nanotherapeutics that regulate the immune response to treat a range of conditions, including cancer, cardiovascular and autoimmune diseases.
Nanotechnology for immunotherapy
Nanotechnology can be applied to empower the immune system’s ability to fight disease, by promoting or inhibiting an immune response, by polarizing macrophage function, or by targeting myeloid cell dynamics. The innovation cascade involves developing biocompatible nanoimmunotherapeutics from natural molecular building blocks and comprises an innovative translational workflow, involving noninvasive imaging for testing on small and large animal disease models.
Meet some of our Researchers
Recent Publications
Our most recent peer reviewed publications
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ratione
Trained immunity
Cell Host and Microbe (2023) -
Matt Timmers,Wouter Peeters,Niels J Hauwert,Cristianne J F Rijcken,Tina Vermonden,Ingrid Dijkgraaf,Rob M J Liskamp
Specific N-terminal attachment of TMTHSI linkers to native peptides and proteins for strain-promoted azide alkyne cycloaddition
Chemical Communications, ChemComm (2023) -
David P Schrijver,Rutger J Röring,Anne de Dreu,Yohana C Toner,Geoffrey Prevot,Bram Priem,Jazz Munitz,Yuri van Elsas,Anthony Azzun,Tom Anbergen
Resolving sepsis-induced immunoparalysis via trained immunity by targeting interleukin-4 to myeloid cells
Nature Biomedical Engineering (2023) -
Matt Timmers,Andi Kipper,Raphael Frey,Stef Notermans,Maksym Voievudskyi,Claire Wilson,Nina Hentzen,Michael Ringle,Clara Bovino,Bernhard Stump
Exploring the Chemical Properties and Medicinal Applications of Tetramethylthiocycloheptyne Sulfoximine Used in Strain-Promoted Azide-Alkyne Cycloaddition Reactions
Pharmaceuticals (2023) -
Bas W.A. Bögels,Bichlien H. Nguyen,David Ward,Levena Gascoigne,David P. Schrijver,Anna Maria Makri Pistikou,Alex Joesaar,Shuo Yang,Ilja K. Voets,Willem J.M. Mulder
DNA storage in thermoresponsive microcapsules for repeated random multiplexed data access
Nature Nanotechnology (2023)
Contact
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Postal address
Jill WillemsenHelix BuildingPostbus 5135600 MB EindhovenNetherlands -
Postal address
Luca de VriesRafael van de Venvan der Hoevenstraat5231PS BrouwershavenNetherlands -
Visiting address
Joris MohanHelix Building (STO 3.39)De Groene Loper 35612 AE EindhovenNetherlands -
Visiting address
Dirk Yükseldr. Jennifer Koçvan Maarensingel8322EH BussumNetherlands -
SecretarySophia Roomde Bruinsteeg9675LR Boer