Roy van der Meel
Department / Institute
Group
RESEARCH PROFILE
Roy van der Meel is Assistant Professor of Precision Medicine at the TU/e's Biomedical Engineering department. His research is focused on developing RNA-based nanotherapeutics to regulate the immune response in a highly precise manner.
ACADEMIC BACKGROUND
Roy van der Meel studied Biomedical Sciences and Drug Innovation at Utrecht University in The Netherlands where he obtained his M.Sc. degree in 2009. He then conducted his Ph.D. research at the Utrecht University Pharmaceutics Department under supervision of Wim Hennink, Gert Storm, Robbert Jan Kok and Raymond Schiffelers. Roy's research focused on developing nanomedicines to inhibit tumor growth and angiogenesis and he obtained his Ph.D. degree in 2013. After obtaining Marie Skłodowska-Curie Action funding from the European Commission and a Veni grant from the Dutch Research Council (NWO), Roy conducted postdoctoral research in the labs of Raymond Schiffelers (University Medical Center Utrecht) and Pieter Cullis (University of British Columbia, Vancouver, BC, Canada). In 2019, Roy was appointed Assistant Professor of Precision Medicine at the TU/e's Biomedical Engineering department. His research is supported by an NWO Vidi grant awarded in 2022.
Recent Publications
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ratione
Trained immunity
Cell Host and Microbe (2023) -
S.R.J. Hofstraat,T. Anbergen,Robby Zwolsman,Ewelina Kluza,Roy van der Meel,Willem J.M. Mulder
A nature-inspired nanodelivery platform for gene silencing in hematopoietic stem and progenitor cells
(2023) -
David P Schrijver,Rutger J Röring,Anne de Dreu,Yohana C Toner,Geoffrey Prevot,Bram Priem,Jazz Munitz,Yuri van Elsas,Anthony Azzun,Tom Anbergen
Resolving sepsis-induced immunoparalysis via trained immunity by targeting interleukin-4 to myeloid cells
Nature Biomedical Engineering (2023) -
Tom Anbergen,Ayla M. Hokke,Anne de Dreu,David P. Schrijver,Koen de Bruin,Yohana C. Toner,Thijs Beldman,Jamie B. Spangler,Tom F.A. de Greef,Francesca Grisoni
Engineering cytokine therapeutics
Nature Reviews. Bioengineering (2023) -
Joslyn Quick,Nancy Dos Santos,Miffy H.Y. Cheng,Nisha Chander,Cedric A. Brimacombe,Jayesh Kulkarni,Roy van der Meel,Yuen Yi C. Tam,Dominik Witzigmann,Pieter R. Cullis
Lipid nanoparticles to silence androgen receptor variants for prostate cancer therapy
Journal of Controlled Release (2022)
Current Educational Activities
Ancillary Activities
- Scientific advisor, TAONas-LUAD project
- Consultancy, Venable LLC
- Consultancy, Servier